Gene information
Official symbol PTPRB
Official full name protein tyrosine phosphatase receptor type B
Gene type protein-coding gene
Chromosome12q15
Previous symbolPTPB
Gene familyFibronectin type III domain containing; Protein tyrosine phosphatases receptor type
Resources
Entrez Gene 5787
HGNC HGNC:9665
Ensembl ENSG00000127329
Vega OTTHUMG00000169499
UCSC uc001swc.6
GO terms: 26 records
GO Description Category LogP Number of genes Detail
GO:0001525 angiogenesis GO Biological Processes -32.8794581 74 More
GO:0001568 blood vessel development GO Biological Processes -43.2646440 106 More
GO:0001933 negative regulation of protein phosphorylation GO Biological Processes -19.8214973 59 More
GO:0001944 vasculature development GO Biological Processes -42.3240404 107 More
GO:0004721 phosphoprotein phosphatase activity GO Molecular Functions -1.31927645 6 More
GO:0006469 negative regulation of protein kinase activity GO Biological Processes -12.6852914 37 More
GO:0006470 protein dephosphorylation GO Biological Processes -1.88765377 8 More
GO:0010563 negative regulation of phosphorus metabolic process GO Biological Processes -21.7837721 71 More
GO:0016311 dephosphorylation GO Biological Processes -2.12115190 11 More
GO:0016788 hydrolase activity, acting on ester bonds GO Molecular Functions -4.57583420 56 More
GO:0030667 secretory granule membrane GO Cellular Components -8.32957622 38 More
GO:0031400 negative regulation of protein modification process GO Biological Processes -17.0986645 70 More
GO:0033673 negative regulation of kinase activity GO Biological Processes -12.5521161 39 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035579 specific granule membrane GO Cellular Components -4.58725293 14 More
GO:0042326 negative regulation of phosphorylation GO Biological Processes -20.6187298 64 More
GO:0042578 phosphoric ester hydrolase activity GO Molecular Functions -4.79997475 34 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0045296 cadherin binding GO Molecular Functions -1.90453590 11 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0045936 negative regulation of phosphate metabolic process GO Biological Processes -21.8424865 71 More
GO:0048514 blood vessel morphogenesis GO Biological Processes -39.8784810 93 More
GO:0050839 cell adhesion molecule binding GO Molecular Functions -14.4506551 68 More
GO:0051348 negative regulation of transferase activity GO Biological Processes -13.2006110 43 More
GO:0070821 tertiary granule membrane GO Cellular Components -3.64814241 11 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
razuprotafib TTD view
sunitinib CIViC 24633157 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg09133028 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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